Pain relief will they ever figure it out

[KGBSkunky]

I noticed yet another study about how cannabis doesn't relieve pain and is just a placebo. I do agree with them that it doesn't relieve pain, for me, but will they ever do a study that is to find out if cannabis allows someone to "control" pain which is just as useful if not more than numbing. Because it does wonders for controlling pain.

Just my opinion try not to flame too hard

 

[boo]

I agree 100%. I’ve gone through more than my fair share of pain in my life and marijuana does nothing to illuminate it. I found that all it does is takes my mind away from it so it’s not as bad but it’s still there. When people tell me that smoking weed cures cancer I just can’t come up with more ignorant term than stupid for the what they’re saying.

 

[KGBSkunky]

I agree 100%. I’ve gone through more than my fair share of pain in my life and marijuana does nothing to illuminate it. I found that all it does is takes my mind away from it so it’s not as bad but it’s still there. When people tell me that smoking weed cures cancer I just can’t come up with more ignorant term than stupid for the what they’re saying.

I wouldn't be so sure about that. Just be sure it's not going to do that for everyone. In fact I can shoot you a percentage range. 15 to 20 percent of the people that take it stand a good change of it actually curing medical issues.

And before you scoff think about this. Cancer runs in my family and I didn't get it with one of the differences between me and them is eat green bananas

 

[pute]

I was in pain until I took my first time. Fine now.

 

[sharonp]

They are suppose to show how they conducted their research. That would be interesting to see what strains were used and what painful conditions people had along with how did they smoke it or ingest it or whatever.

 

[boo]

Cancer does not run in my family yet. I suffered through it. I’m sure I’m a lot older than you and I probably smoked more pot in my life than you’ve ever seen but that didn’t stop the cancer from coming into my life and wreaking havoc. I won’t be disrespectful about your percentages but you’re painting with such a broadbrush it’s not applicable. I would love to believe marijuana can cure disease, but there is absolutely no clinical proof that it can.

 

[KGBSkunky]

Cancer does not run in my family yet. I suffered through it. I’m sure I’m a lot older than you and I probably smoked more pot in my life than you’ve ever seen but that didn’t stop the cancer from coming into my life and wreaking havoc. I won’t be disrespectful about your percentages but you’re painting with such a broadbrush it’s not applicable. I would love to believe marijuana can cure disease, but there is absolutely no clinical proof that it can.

I'm fairly old but looking at statistics around the world the percentage of people that use is generally between 15 to 20 percent. I know a lot of people that tried it and just didn't care about it. Looking at Colorado when they first legalized percentage was 12.7 and after five years 15.7. Looking at Canada it was 15 percent two years after legalization. And for the old tried and true the guys I knew from the Vietnam was all said you drank or drugged and the split was, at a guess, 80/20

My theory is around 15 to 20 percent of people are genetically disposed and it does something different than with the other 80 percent
As for how they conducted their research not sure it matters that much. Every study I have seen compares cannabis to opioids with the tests being something like Spicoli banging his head with a shoe. Opioids will do that cannabis won't

 

[boo]

I guess I am misunderstanding your post. I thought you were talking about cannabis, curing diseases. You’re referencing opioids has zero correlation with curing anything as opiates just mask pain. I have a lot of experience with both marijuana and opiates, and neither one will cure anything that I’ve had nor stop the pain when it’s as intense as it has been. I would like to see some legitimate studies on what marijuana can do to help eliminate disease. I think it might be wishful thinking on your part but then again, I’m not a rocket scientist so I might be wrong. I will go on record as saying that I am an expert when it comes to dealing with intense pain. I was the first person in the nation to do a trial on extremely high milligram opiates that are time released I found they didn’t work on me, as well as a standard opioid did. I was cut so severely the only thing that was holding my top and bottom half together was my spine.

 

[WeedHopper]

My question would be,,,, why do so many ppl that smoke weed get cancer if weed helps cure cancer. Not saying CBD or THC might not help certain cancers but I just haven't seen it and I'm 67. I will say there is a possibility that a topical might help with skin cancer but I'd have to see more studies on something like that.
Now don't get me wrong. I realize that lifestyle has a lot to do with cancers such as Lung cancer. Smoking cigarettes is a big problem but so was pesticides that's been in our lives for so long. I don't know anyone personally that benefited from weed when it came to cancer,,but that's just me.
As for pain relief I have never had weed help me with pain. I've been shot,,run over twice while riding my Harley and many more things such as open heart surgery. Weed didn't not do shit for my pain. Pain killers helped but that was it.

 

[joeb631a]

Cancer does not run in my family yet. I suffered through it. I’m sure I’m a lot older than you and I probably smoked more pot in my life than you’ve ever seen but that didn’t stop the cancer from coming into my life and wreaking havoc. I won’t be disrespectful about your percentages but you’re painting with such a broadbrush it’s not applicable. I would love to believe marijuana can cure disease, but there is absolutely no clinical proof that it can.

B4 I started smoking pot 52 years ago I was lost.52 years latter Im still lost but having a better time being lost ....

 

[Unca Walt]

I would love to believe marijuana can cure disease, but there is absolutely no clinical proof that it can.

@boo --

Just this very morning after reading this thread, I discovered a whole raft of studies from the National Institute of Health (NIH) regarding the relationship between cannabis and cancer cure/abatement.

I'll admit I was really surprised. No, more like gobsmacked.

I had no fargin clue that so many serious studies have been made. If only one in ten are counted, it is still a huge pile of work that has been done regarding cannabis and its effect on cancer in general (and in specifics, too).

I, too, did not think there was anything but wild talk. I now think otherwise. Lookit this -- Specific papers written on cures at NIH:

Brain Cancer

http://www.nature.com/bjc/journal/v95/n2/abs/6603236a.html

Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor - PubMed

The development of new therapeutic strategies is essential for the management of gliomas, one of the most malignant forms of cancer. We have shown previously that the growth of the rat glioma C6 cell line is inhibited by psychoactive cannabinoids (I. Galve-Roperh et al., Nat. Med., 6: 313-319...

www.ncbi.nlm.nih.gov

Neuroprotection by Δ9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity

Excitotoxicity is a paradigm used to explain the biochemical events in both acute neuronal damage and in slowly progressive, neurodegenerative diseases. Here, we show in a longitudinal magnetic resonance imaging study that Δ9-tetrahydrocannabinol (Δ9-THC), the main active compound in marijuana...

www.jneurosci.org

Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines

Recently, cannabinoids (CBs) have been shown to possess antitumor properties. Because the psychoactivity of cannabinoid compounds limits their medicinal usage, we undertook the present study to evaluate the in vitro antiproliferative ability of cannabidiol (CBD), a nonpsychoactive cannabinoid...

jpet.aspetjournals.org

http://mct.aacrjournals.org/content/10/1/90.abstract

--------------------------------------------------------------

Mouth and Throat Cancer

Cannabinoids inhibit cellular respiration of human oral cancer cells - PubMed

These results show the cannabinoids are potent inhibitors of Tu183 cellular respiration and are toxic to this highly malignant tumor.

www.ncbi.nlm.nih.gov

--------------------------------------------------------------

Breast Cancer

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis - PubMed

Invasion and metastasis of aggressive breast cancer cells are the final and fatal steps during cancer progression. Clinically, there are still limited therapeutic interventions for aggressive and metastatic breast cancers available. Therefore, effective, targeted, and non-toxic therapies are...

www.ncbi.nlm.nih.gov

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells - PubMed

Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is the least understood genetically. Clinically, there are still limited therapeutic interventions for aggressive and metastatic breast cancers available. Clearly, effective and...

www.ncbi.nlm.nih.gov

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion - PubMed

This study provides novel insights into the crosstalk between CB(2) and CXCR4/CXCL12-signaling pathways in the modulation of breast tumor growth and metastasis. Furthermore, these studies indicate that CB(2) receptors could be used for developing innovative therapeutic strategies against breast...

www.ncbi.nlm.nih.gov

Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

jpet.aspetjournals.org

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition - Molecular Cancer

Background ErbB2-positive breast cancer is characterized by highly aggressive phenotypes and reduced responsiveness to standard therapies. Although specific ErbB2-targeted therapies have been designed, only a small percentage of patients respond to these treatments and most of them eventually...

www.molecular-cancer.com

Cannabinoids: a new hope for breast cancer therapy? - PubMed

Breast cancer is a very common disease that affects approximately 1 in 10 women at some point in their lives. Importantly, breast cancer cannot be considered a single disease as it is characterized by distinct pathological and molecular subtypes that are treated with different therapies and have...

www.ncbi.nlm.nih.gov

http://www.pnas.org/content/95/14/8375.full.pdf+htm

-----------------------------------------------------------------

Lung Cancer

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1 - PubMed

Cannabinoids inhibit cancer cell invasion via increasing tissue inhibitor of matrix metalloproteinases-1 (TIMP-1). This study investigates the role of intercellular adhesion molecule-1 (ICAM-1) within this action. In the lung cancer cell lines A549, H358, and H460, cannabidiol (CBD; 0.001-3 μM)...

www.ncbi.nlm.nih.gov

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis - PubMed

Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide; however, only limited therapeutic treatments are available. Hence, we investigated the role of cannabinoid receptors, CB1 and CB2, as novel therapeutic targets against NSCLC. We observed expression of CB1 (24%)...

www.ncbi.nlm.nih.gov

http://www.nature.com/onc/journal/v27/n3/abs/1210641a.htm

---------------------------------------------------------------------

Uterine, Testicular, and Pancreatic Cancers

Cannabis and Cannabinoids (PDQ®)–Health Professional Version

Cannabis has been used medicinally for millennia, but has not been approved by the U.S. Food and Drug Administration to treat any medical condition. Cannabinoids are the components in cannabis; some are commercially available to treat symptoms. Get detailed information in this clinician summary.

www.cancer.gov

http://cancerres.aacrjournals.org/content/66/13/6748.abstract

---------------------------------------------------------------------

Prostate Cancer

Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production - PubMed

The potent anti-proliferative and cytotoxic effects of ANA on metastatic prostatic cancer cells might provide basis for the design of new therapeutic agents for effective treatment of recurrent and invasive prostatic cancers.

www.ncbi.nlm.nih.gov

The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications

Prostate cancer is a global public health problem, and it is the most common cancer in American men and the second cause for cancer-related death. Experimental evidence shows that prostate tissue possesses cannabinoid receptors and their stimulation results ...

www.ncbi.nlm.nih.gov

Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms - PubMed

These data support the clinical testing of CBD against prostate carcinoma.

www.ncbi.nlm.nih.gov

------------------------------------------------------------------------------

Colorectal Cancer

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer - PubMed

Colon cancer affects millions of individuals in Western countries. Cannabidiol, a safe and non-psychotropic ingredient of Cannabis sativa, exerts pharmacological actions (antioxidant and intestinal antinflammatory) and mechanisms (inhibition of endocannabinoid enzymatic degradation) potentially...

www.ncbi.nlm.nih.gov

-----------------------------------------------------------------------------

Ovarian Cancer

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084

-----------------------------------------------------------------------------

Blood Cancer

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease - PubMed

In the current study, we examined whether ligation of CB2 receptors would lead to induction of apoptosis in tumors of immune origin and whether CB2 agonist could be used to treat such cancers. Exposure of murine tumors EL-4, LSA, and P815 to delta-9-tetrahydrocannabinol (THC) in vitro led to a...

www.ncbi.nlm.nih.gov

Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria - PubMed

Plant-derived cannabinoids, including Delta9-tetrahydrocannabinol (THC), induce apoptosis in leukemic cells, although the precise mechanism remains unclear. In the current study, we investigated the effect of THC on the upstream and downstream events that modulate the extracellular...

www.ncbi.nlm.nih.gov

http://onlinelibrary.wiley.com/doi/10.1002/ijc.23584/abstract

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma

We have recently shown that cannabinoids induce growth inhibition and apoptosis in mantle cell lymphoma (MCL), a malignant B-cell lymphoma that expresses high levels of cannabinoid receptor types 1 and 2 (CB1 and CB2). In the current study, the role of each receptor and the signal transduction...

molpharm.aspetjournals.org

-----------------------------------------------------------------------------

Skin Cancer

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors - PubMed

Nonmelanoma skin cancer is one of the most common malignancies in humans. Different therapeutic strategies for the treatment of these tumors are currently being investigated. Given the growth-inhibiting effects of cannabinoids on gliomas and the wide tissue distribution of the two subtypes of...

www.ncbi.nlm.nih.gov

----------------------------------------------------------------------------

Bladder Cancer
http://www.medscape.com/viewarticle/803983 (Sign-up required to view study)
----------------------------------------------------------------------------

Cancer in General
Inhibition of tumor angiogenesis by cannabinoids - PubMed

Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas - PubMed

Cannabinoids inhibit tumor angiogenesis in mice, but the mechanism of their antiangiogenic action is still unknown. Because the vascular endothelial growth factor (VEGF) pathway plays a critical role in tumor angiogenesis, here we studied whether cannabinoids affect it. As a first approach, cDNA...

www.ncbi.nlm.nih.gov

Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas - PubMed

Cannabinoids inhibit tumor angiogenesis in mice, but the mechanism of their antiangiogenic action is still unknown. Because the vascular endothelial growth factor (VEGF) pathway plays a critical role in tumor angiogenesis, here we studied whether cannabinoids affect it. As a first approach, cDNA...

www.ncbi.nlm.nih.gov

 

[SubmarineGirl]

I’ve read enough positive studies to feel confident that cannabis will help fight cancer. That’s just my opinion. May have to donate my body to the cannabis research when I’m done with it to give them something to research.

 

[Unca Walt]

I’ve read enough positive studies to feel confident that cannabis will help fight cancer. That’s just my opinion. May have to donate my body to the cannabis research when I’m done with it to give them something to research.

I am pretty much the definition of a cyborg -- using "Terminator" as a baseline. Lotsa metal all over. Not only that, but my left knee (which had been behind my head) has some parts of me in it donated from other places.

I have willed my body to science.

The scientists are contesting the will.

 

[bigsur51]

Boo --

Just this very morning after reading this thread, I discovered a whole raft of studies from the National Institute of Health (NIH) regarding the relationship between cannabis and cancer cure/abatement.

I'll admit I was really surprised. No, more like gobsmacked.

I had no fargin clue that so many serious studies have been made. If only one in ten are counted, it is still a huge pile of work that has been done regarding cannabis and its effect on cancer in general (and in specifics, too).

I, too, did not think there was anything but wild talk. I now think otherwise. Lookit this -- Specific papers written on cures at NIH:

Brain Cancer

http://www.nature.com/bjc/journal/v95/n2/abs/6603236a.html

Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor - PubMed

The development of new therapeutic strategies is essential for the management of gliomas, one of the most malignant forms of cancer. We have shown previously that the growth of the rat glioma C6 cell line is inhibited by psychoactive cannabinoids (I. Galve-Roperh et al., Nat. Med., 6: 313-319...

www.ncbi.nlm.nih.gov

Neuroprotection by Δ9-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-Induced In Vivo Excitotoxicity

Excitotoxicity is a paradigm used to explain the biochemical events in both acute neuronal damage and in slowly progressive, neurodegenerative diseases. Here, we show in a longitudinal magnetic resonance imaging study that Δ9-tetrahydrocannabinol (Δ9-THC), the main active compound in marijuana...

www.jneurosci.org

Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines

Recently, cannabinoids (CBs) have been shown to possess antitumor properties. Because the psychoactivity of cannabinoid compounds limits their medicinal usage, we undertook the present study to evaluate the in vitro antiproliferative ability of cannabidiol (CBD), a nonpsychoactive cannabinoid...

jpet.aspetjournals.org

http://mct.aacrjournals.org/content/10/1/90.abstract

--------------------------------------------------------------

Mouth and Throat Cancer

Cannabinoids inhibit cellular respiration of human oral cancer cells - PubMed

These results show the cannabinoids are potent inhibitors of Tu183 cellular respiration and are toxic to this highly malignant tumor.

www.ncbi.nlm.nih.gov

--------------------------------------------------------------

Breast Cancer

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis - PubMed

Invasion and metastasis of aggressive breast cancer cells are the final and fatal steps during cancer progression. Clinically, there are still limited therapeutic interventions for aggressive and metastatic breast cancers available. Therefore, effective, targeted, and non-toxic therapies are...

www.ncbi.nlm.nih.gov

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells - PubMed

Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is the least understood genetically. Clinically, there are still limited therapeutic interventions for aggressive and metastatic breast cancers available. Clearly, effective and...

www.ncbi.nlm.nih.gov

Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion - PubMed

This study provides novel insights into the crosstalk between CB(2) and CXCR4/CXCL12-signaling pathways in the modulation of breast tumor growth and metastasis. Furthermore, these studies indicate that CB(2) receptors could be used for developing innovative therapeutic strategies against breast...

www.ncbi.nlm.nih.gov

Anti-tumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

jpet.aspetjournals.org

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition - Molecular Cancer

Background ErbB2-positive breast cancer is characterized by highly aggressive phenotypes and reduced responsiveness to standard therapies. Although specific ErbB2-targeted therapies have been designed, only a small percentage of patients respond to these treatments and most of them eventually...

www.molecular-cancer.com

Cannabinoids: a new hope for breast cancer therapy? - PubMed

Breast cancer is a very common disease that affects approximately 1 in 10 women at some point in their lives. Importantly, breast cancer cannot be considered a single disease as it is characterized by distinct pathological and molecular subtypes that are treated with different therapies and have...

www.ncbi.nlm.nih.gov

http://www.pnas.org/content/95/14/8375.full.pdf+htm

-----------------------------------------------------------------

Lung Cancer

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1 - PubMed

Cannabinoids inhibit cancer cell invasion via increasing tissue inhibitor of matrix metalloproteinases-1 (TIMP-1). This study investigates the role of intercellular adhesion molecule-1 (ICAM-1) within this action. In the lung cancer cell lines A549, H358, and H460, cannabidiol (CBD; 0.001-3 μM)...

www.ncbi.nlm.nih.gov

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis - PubMed

Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide; however, only limited therapeutic treatments are available. Hence, we investigated the role of cannabinoid receptors, CB1 and CB2, as novel therapeutic targets against NSCLC. We observed expression of CB1 (24%)...

www.ncbi.nlm.nih.gov

http://www.nature.com/onc/journal/v27/n3/abs/1210641a.htm

---------------------------------------------------------------------

Uterine, Testicular, and Pancreatic Cancers

Cannabis and Cannabinoids (PDQ®)–Health Professional Version

Cannabis has been used medicinally for millennia, but has not been approved by the U.S. Food and Drug Administration to treat any medical condition. Cannabinoids are the components in cannabis; some are commercially available to treat symptoms. Get detailed information in this clinician summary.

www.cancer.gov

http://cancerres.aacrjournals.org/content/66/13/6748.abstract

---------------------------------------------------------------------

Prostate Cancer

Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production - PubMed

The potent anti-proliferative and cytotoxic effects of ANA on metastatic prostatic cancer cells might provide basis for the design of new therapeutic agents for effective treatment of recurrent and invasive prostatic cancers.

www.ncbi.nlm.nih.gov

The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications

Prostate cancer is a global public health problem, and it is the most common cancer in American men and the second cause for cancer-related death. Experimental evidence shows that prostate tissue possesses cannabinoid receptors and their stimulation results ...

www.ncbi.nlm.nih.gov

Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms - PubMed

These data support the clinical testing of CBD against prostate carcinoma.

www.ncbi.nlm.nih.gov

------------------------------------------------------------------------------

Colorectal Cancer

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer - PubMed

Colon cancer affects millions of individuals in Western countries. Cannabidiol, a safe and non-psychotropic ingredient of Cannabis sativa, exerts pharmacological actions (antioxidant and intestinal antinflammatory) and mechanisms (inhibition of endocannabinoid enzymatic degradation) potentially...

www.ncbi.nlm.nih.gov

-----------------------------------------------------------------------------

Ovarian Cancer

http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1084

-----------------------------------------------------------------------------

Blood Cancer

Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease - PubMed

In the current study, we examined whether ligation of CB2 receptors would lead to induction of apoptosis in tumors of immune origin and whether CB2 agonist could be used to treat such cancers. Exposure of murine tumors EL-4, LSA, and P815 to delta-9-tetrahydrocannabinol (THC) in vitro led to a...

www.ncbi.nlm.nih.gov

Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria - PubMed

Plant-derived cannabinoids, including Delta9-tetrahydrocannabinol (THC), induce apoptosis in leukemic cells, although the precise mechanism remains unclear. In the current study, we investigated the effect of THC on the upstream and downstream events that modulate the extracellular...

www.ncbi.nlm.nih.gov

http://onlinelibrary.wiley.com/doi/10.1002/ijc.23584/abstract

Cannabinoid Receptor-Mediated Apoptosis Induced by R(+)-Methanandamide and Win55,212-2 Is Associated with Ceramide Accumulation and p38 Activation in Mantle Cell Lymphoma

We have recently shown that cannabinoids induce growth inhibition and apoptosis in mantle cell lymphoma (MCL), a malignant B-cell lymphoma that expresses high levels of cannabinoid receptor types 1 and 2 (CB1 and CB2). In the current study, the role of each receptor and the signal transduction...

molpharm.aspetjournals.org

-----------------------------------------------------------------------------

Skin Cancer

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors - PubMed

Nonmelanoma skin cancer is one of the most common malignancies in humans. Different therapeutic strategies for the treatment of these tumors are currently being investigated. Given the growth-inhibiting effects of cannabinoids on gliomas and the wide tissue distribution of the two subtypes of...

www.ncbi.nlm.nih.gov

----------------------------------------------------------------------------

Bladder Cancer
http://www.medscape.com/viewarticle/803983 (Sign-up required to view study)
----------------------------------------------------------------------------

Cancer in General
Inhibition of tumor angiogenesis by cannabinoids - PubMed

Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas - PubMed

Cannabinoids inhibit tumor angiogenesis in mice, but the mechanism of their antiangiogenic action is still unknown. Because the vascular endothelial growth factor (VEGF) pathway plays a critical role in tumor angiogenesis, here we studied whether cannabinoids affect it. As a first approach, cDNA...

www.ncbi.nlm.nih.gov

Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas - PubMed

Cannabinoids inhibit tumor angiogenesis in mice, but the mechanism of their antiangiogenic action is still unknown. Because the vascular endothelial growth factor (VEGF) pathway plays a critical role in tumor angiogenesis, here we studied whether cannabinoids affect it. As a first approach, cDNA...

www.ncbi.nlm.nih.gov

BAM!…….there it is

imma gonna error on the side of caution and continue to medicate with cannabis both orally and topically

if fact i better double down on my dosages every chance i get cause at my age i never know if it will be my last toke



FIRE IN THE HOLE!

 

[KGBSkunky]

Sorry tried to reply on the wrong device. If you are unaware of the above studies then you may not know about the mother of all studies which they quickly looked away from and hardly acknowledge exists. Only one patient is left in the program although 2 are still alive the other happened to live in Oregon and doesn't want the low grade crap from Mississippi. His name is Irvin Rosenfeld. The government started the program with 13 people who had conditions that would disable or kill them in just a few years putting the notion that it actually cures things. Well they were right and wrong. It did not cure them but rather allowed all 13 to live much longer than the average person taking prescription medication. Check it out

Note the program started in 1991and was supposed to be a big win in the argument to remove it from schedule 1. What a pie in the face

Only One Federal Cannabis Patient Left as Elvy Musikka Exits IND Program

Glaucoma sufferer Elvy Musikka, who received 300 joints per month since 1988 as part of the government's Compassionate IND program, has departed it, leaving Irvin Rosenfeld as the last remaining federal medical-marijuana patient.

www.celebstoner.com

 

[Hippie420]

I’ve read enough positive studies to feel confident that cannabis will help fight cancer. That’s just my opinion. May have to donate my body to the cannabis research when I’m done with it to give them something to research.

Maybe orally, but I'm bettin' smoking it doesn't. Anything that goes into your lungs that ain't clean air ain't good for ya.
If'n they'll give my gold teeth to the Old Hen, I'd donate mine, too.

 

[Hippie420]

Only thing that'll truly stop pain is a grave blanket. Pain lets you know that you're still alive.

 

[Loolagigi2]

Everything can kill you, so you might as well enjoy what you do while you are here.

 

[sharonp]

I use opioids and cannabis for pain. Cannabis is great for my migraines. The only problems is how much I have to smoke sometimes for it to be effective. You have to experiment with the different strains also.

 

[Unca Walt]

Maybe orally, but I'm bettin' smoking it doesn't. Anything that goes into your lungs that ain't clean air ain't good for ya.
If'n they'll give my gold teeth to the Old Hen, I'd donate mine, too.

I don't think the guy mentioned really ate 300 joints a month for years...

There are inhalents that go right into your lungs and help you. Decongestion, a direct medicine to your bloodstream, a whole bunch.

"...classification system lists four general categories of inhalants — volatile solvents, aerosols, gases, and nitrites..."

I'm 82. Would not have gotten this far, and in such active health** without cannabis. Being with a bag of smoke enables me to not only bear, but ignore pain that otherwise cripple me. <-- The double-plus part? Being active means I stay healthy and fit -- rather than bent over and curled up. Chalk up that status to the cannabis WIN column.

**See crossbow thread
Now go light the fukk up and enjoy.

It will make you live longer and happier and healthier.