Something for you to ponder about

[123lsd]

Marijuana: interaction with the estrogen receptor
MA Sauer, SM Rifka, RL Hawks, GB Cutler and DL Loriaux


Crude marijuana extract competed with estradiol for binding to the estrogen receptor of rat uterine cytosol. Condensed marijuana smoke also competed with estradiol for its receptor. Pure delta 9- tetrahydrocannabinol, however, did not interact with the estrogen receptor. Ten delta 9-tetrahydrocannabinol metabolites also failed to compete with estradiol for its receptor. Of several other common cannabinoids tested, only cannabidiol showed any estrogen receptor binding. This was evident only at very high concentrations of cannabidiol. Apigenin, the aglycone of a flavinoid phytoestrogen found in cannabis, displayed high affinity for the estrogen receptor. To assess the biological significance of these receptor data, estrogen activity was measured in vivo with the uterine growth bioassay, using immature rats. Cannabis extract in large doses exhibited neither estrogenic nor antiestrogenic effects. Thus, although estrogen receptor binding activity was observed in crude marijuana extract, marijuana smoke condensate and several known components of cannabis, direct estrogenic activity of cannabis extract could not be demonstrated in vivo.

 

[GrewUp To ScrewUp]

***..

 

[Growdude]

Im not to worried about my estrogen levels

 

[123lsd]

it means if you smoke weed, your gonna grow a savage vagina!

 

[Stoney Bud]

So, 123lsd, what do you think of what you just posted?

 

[SmokinMom]

Too many big words in there Smokey. It made my head hurt!!! Can I have the cliffnotes version?

 

[Meg]

I couldn't even read that man.

 

[Fretless]

Yeah that's a mindbender. I waded through it. Interesting though. So in Rats, cannabis smoke had no effect on estrogen receptors for the mothers or the offspring. Only when 'crude cannabis extract' was used did this happen. I'm not sure what they mean by crude extract, probably something like gunk.

 

[LaserKittensGoPewPew]

How about explaining this in your own terms. Posting up a bunch of medical jargon means absolutely nothing to any of us because nearly all of us don't understand the terminology behind it. Since you're in the "know" maybe you can shed some light on it for the rest of us.