I'm a therapist in a mental health program in West Virgina. Yesterday, I did an "intake" on a guy who had been busted and sent to prison for cultivation. His position was that our state's economy was so unavailable to common folk that cultivation was the only opportunity -- he's probably correct. Anyway, since he was manic (bipolar disorder) he went on and on about cloning, but admitted that potency declines from one generation to the next. He also advocated for use as a more effective treatment than big pharmaceutical for his condition, hardly the first. He was hinting for Rx, but WV is not there, yet.
Since my advocacy is child abuse prevention rather than legalization (read Rarity from the Hollow to find out about an often overlooked micro nutrient from a novel strongly relevant to this site and which raises funds for nonprofit cause), I had to redirect the dialogue during this intake to not failing a urine screen on parole.
Personally and unfairly, I've not been able to smoke for well over a decade due to random. So, now I have high liver enzymes. I got this guy to commit to therapy.
Bottom line according to him as expert, clone but start with new seeds after a few generations. Ensure totally female with the new seeds (no hermaphrodite -- it can be tricky), and then repeat the process. The rooting is irrelevant.
The THC measure on his stash when he got busted was almost unbelievable and maybe the lab lied (you know how news talks about busts by weight but it includes leaves, stems, and sometimes attached dirt)! Good luck, but most importantly be safe. No high is worth what this great guy who had never hurt anything went thru.
Mental illness is not a character flaw, but a genetic body chemistry unfairness. He and I are now connected and I will do my best to assist him stay free, which means no smoke.