CBD extraction/FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS

Discussion in 'Medical Marijuana' started by 7greeneyes, Mar 26, 2014.

  1. Mar 26, 2014 #1

    7greeneyes

    7greeneyes

    7greeneyes

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    Found this for Rose, in case she was interested, (and anyone else) too...


    hMPp://cannabisinternational.org/info/Fractionating-Cannabinoids.pdf




    ACCESSING 0.5 to 2.0 GRAMS CBD

    FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS

    Patients can use heat to fractionate or separate the active ingredients in cannabis by their vaporization or boiling points. In particular for those patients that need relief from pain, inflammation, muscle spasm and or anxiety during the daytime CBD or Cannabidiol is a non-psychoactive cannabinoid that once separated from THC. CBD is a uniquely potent antioxidant that can cross the blood-brain barrier in addition to CBD’s ability to reduce anxiety, pain and inflammation outside the CNS (Central Nervous System). Interestingly, CBD is claimed in United States Patent 6,630,507, which notably has been assigned to the United States of America Dept of Health and Human Services. In particular note the definitions of Oxidative Associated Diseases for which CBD is ideally suited. Once convinced of the utility of this non-psychoactive phyto-cannabinoid, the challenge is how to extract it from cannabis. Of the strains in this county Northern Lights has the highest CBD concentration at 1.0%. Since a pound of cannabis weighs 454 grams, there is 4.5 grams of CBD available. Another strain, White Russian has 2.0% CBD. White Russian is reportedly sensitive to mold but if compatible with your environment, it would be a 100% improvement in CBD concentration. While some might raise their eyebrows at the low amount of CBD present per pound of cannabis, it is important to know that there is 10 to 100 times more CBD per pound of cannabis than Vit C per pound of fresh oranges, for oranges 3 months old it would require 20 to 200 times as much raw material to produce an equivalent 500 mg daily dose.

    An article in The Journal of Autoimmunity showed that at particular mouse strain that develops diabetes 86% of the time and is the animal model on which oral and injectable anti-diabetic medications are tested, when given 5 mg/kg body weight per day, 60% DID NOT GO ON TO DEVELOP DIABETES. This would have to be the greatest demonstration of an ‘ounce’ of prevention is worth a pound of cure. There was poster presented at the International Cannabinoid Research Society meeting this last summer that used a dose of 10 mg/ kg which would be equivalent to 1,000 mg / day for 190 pound patient.

    Specifically, since Delta 9 THC vaporizes at 157 degrees centigrade and CBD vaporizes at 188 degrees centigrade, this difference can be used to separate these components. Given the predominance of THC (94% of all cannabinoids present) it is necessary to lower the THC content before collecting the CBD or the level of intoxication is so prohibitive as to prevent access to an adequate amount of CBD. The most efficient approach is to use a variable temperature heat gun. This can be calibrated the heat gun to 166 degree centigrade with the Fluke Digital Thermometer available in the waiting room. At this temperature THC is converted into a vapor and removed. Now you have pre-heated low THC cannabis which can be placed in a collection vaporizer such as a Volcano set at the 6 position or if you have a digital at 190 degrees centigrade to convert CBD from a liquid to a vapor. If there is too much residual THC effect you can raise the preheat temperature to 176 degrees centigrade because a few strains do have some Delta 8 THC, which vaporizes at 175 degrees compared to Delta 9, which vaporizes at 157 degrees centigrade. Please note that I carry a Fluke digital thermometer with which you can calibrate your variable temperature heat gun.

    Alternatively the high CBD cannabis created by stripping out the THC can be used by any means if you do have access to a collecting vaporizer. The amount of THC removed is a function of how finely the cannabis was ground to increase the surface area and how long it is heated. It requires a shift in thinking in that there can be powerful medical benefits without the familiar THC effect, for many older patients this can be comforting information. Once again to develop an appreciation for the breadth of medical utility attributed to CBD please review the patent currently held by the United States a copy of which is available at www . LeavesOf Grass.info.
     
  2. Mar 26, 2014 #2

    7greeneyes

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    Δ-9-tetrahydrocannabinol (THC)
    Boiling point:157*C / 314.6 degree Fahrenheit
    Properties: Euphoriant, Analgesic, Antiinflammatory, Antioxidant, Antiemetic

    cannabidiol (CBD)
    Boiling point: 160-180*C / 320-356 degree Fahrenheit
    Properties: Anxiolytic, Analgesic, Antipsychotic, Antiinflammatory, Antioxidant, Antispasmodic

    Cannabinol (CBN)
    Boiling point: 185*C / 365 degree Fahrenheit
    Properties: Oxidation, breakdown, product, Sedative, Antibiotic

    cannabichromene (CBC)
    Boiling point: 220*C / 428 degree Fahrenheit
    Properties: Antiinflammatory, Antibiotic, Antifungal

    Δ-8-tetrahydrocannabinol (Δ-8-THC)
    Boiling point: 175-178*C / 347-352.4 degree Fahrenheit
    Properties: Resembles Δ-9-THC, Less psychoactive, More stable Antiemetic

    tetrahydrocannabivarin (THCV)
    Boiling point: < 220*C / <428 degree Fahrenheit
    Properties: Analgesic, Euphoriant



    Terpenoid essential oils, their boiling points, and properties

    β-myrcene
    Boiling point: 166-168*C / 330.8-334.4 degree Fahrenheit
    Properties: Analgesic. Antiinflammatory, Antibiotic, Antimutagenic

    β-caryophyllene
    Boiling point: 119*C / 246.2 degree Fahrenheit
    Properties: Antiinflammatory, Cytoprotective (gastric mucosa), Antimalarial

    d-limonene
    Boiling point: 177*C / 350.6 degree Fahrenheit
    Properties: Cannabinoid agonist?, Immune potentiator, Antidepressant, Antimutagenic

    linalool
    Boiling point: 198*C / 388.4 degree Fahrenheit
    Properties: Sedative, Antidepressant, Anxiolytic, Immune potentiator

    pulegone
    Boiling point: 224*C / 435.2 degree Fahrenheit
    Properties: Memory booster?, AChE inhibitor, Sedative, Antipyretic

    1,8-cineole (eucalyptol)
    Boiling point: 176*C / 348.8 degree Fahrenheit
    Properties: AChE inhibitor, Increases cerebral, blood flow, Stimulant, Antibiotic, Antiviral, Antiinflammatory, Antinociceptive

    α-pinene
    Boiling point: 156*C / 312.8 degree Fahrenheit
    Properties: Antiinflammatory, Bronchodilator, Stimulant, Antibiotic, Antineoplastic, AChE inhibitor

    α-terpineol
    Boiling point: 217-218*C / 422.6-424.4 degree Fahrenheit
    Properties: Sedative, Antibiotic, AChE inhibitor, Antioxidant, Antimalarial

    terpineol-4-ol
    Boiling point: 209*C / 408.2 degree Fahrenheit
    Properties: AChE inhibitor. Antibiotic

    p-cymene
    Boiling point: 177*C / 350.6 degree Fahrenheit
    Properties: Antibiotic, Anticandidal, AChE inhibitor

    borneol
    Boiling point: 210*C / 410 degree Fahrenheit
    Properties: Antibiotic, Δ-3-carene 0.004% 168 Antiinflammatory

    Δ-3-carene
    Boiling point: 168*C / 334.4 degree Fahrenheit
    Properties: Antiinflammatory



    Flavonoid and phytosterol components, their boiling points, and properties

    apigenin
    Boiling point: 178*C / 352.4 degree Fahrenheit
    Properties: Anxiolytic, Antiinflammatory, Estrogenic

    quercetin
    Boiling point: 250*C / 482 degree Fahrenheit
    Properties: Antioxidant, Antimutagenic, Antiviral, Antineoplastic

    cannflavin A
    Boiling point: 182*C / 359.6 degree Fahrenheit
    Properties: COX inhibitor, LO inhibitor

    β-sitosterol
    Boiling point: 134*C / 273.2 degree Fahrenheit
    Properties: Antiinflammatory, 5-α-reductase, inhibitor
     
  3. Mar 26, 2014 #3

    Rosebud

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    WOW WOW WOW...now i need to read it again and see if i can understand it better..thank you so much!
     
  4. Mar 26, 2014 #4

    Rosebud

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    I heard a doctor say that in ten years we would all be taking cbd capsules. And the US gov has the patent... great...:~(
     
  5. Mar 26, 2014 #5

    7greeneyes

    7greeneyes

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    yup, heard the same thing.

    How wrong is that? They've known about it this whole time and have kept it under lock and key so to speak.

    And here I thought that was just hippy rhetoric.
     
  6. Mar 26, 2014 #6

    Rosebud

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    I did too, exactly hippy rhetoric. Maybe i better start considering conspiracy theory.
     
  7. Mar 26, 2014 #7

    ArtVandolay

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    OUCH I HAVE A HEADACHE WE NEED A SPECIAL FORUM FOR POSTs WITH WORDS LONGER THAN 7 CHARACTERS AND WORDS THAT END IN OIDS AND OLS!

    Just kidding, 7GReeny :) but I alread knew all that :rofl: and was about to post something similar, but you beat me to it. Thanks :)
     
  8. Mar 26, 2014 #8

    Rosebud

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    God, i Love Art!
     
  9. Mar 27, 2014 #9

    Rosebud

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    I tried to get to read the US Patent...but couldn't get to it....leaves of green.info. org?

    We can have live links here now, if you want to post it again 7G.... I sure appreciate you doing this.
     
  10. Mar 27, 2014 #10

    7greeneyes

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  11. Mar 28, 2014 #11

    ShOrTbUs

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    i'd also like to add that anyone interested in producing quality concentrates, tintures, and such should seriously consider buying professional equipment. while i absolutely loved the read, it does leave out quite a bit of info on the subject. for instance, heating cannabis will also destroy quite a bit of the cannabinoids in the process of decarboxilation. BUT when placed under a vacuum you can lower the temps astronomically. delta 9 thc decarbs at 157F, but when placed under a vacuum it decarbs at just 23F. thats right, thc will boil at freezing temps. this process allows you to extract 100% of the cannabinoids available.

    at the moment vacuum fractionating and super critical c02 extraction are the best methods available.
     
  12. Mar 28, 2014 #12

    Rosebud

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    I really wish i understood what you just said Shortbus....

    what professional equipment are we thinking about? And vacuum? I am confused about boiling points. When it says somethings boiling point is 312 degrees, is that when it is ruined? Or that when the cbds/thc etc is decarbed?
     
  13. Mar 28, 2014 #13

    7greeneyes

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    This is meant as a layman introduction to cbd isolation. thc stripping through super critical fluidic extraction is different beast all together.
     
  14. May 15, 2014 #14

    lindseyj

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    Most cannabinoids are not water soluble, therefore they needs to be dissolved in solvent in oder to extract them.The science of cannabis concentrate extraction functions on the solubility of the cannabinoids.
     
  15. May 15, 2014 #15

    Kindbud

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    very interesting had to reread it :cool2:
     
  16. May 16, 2014 #16

    TrollMaster5000

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    i read one that DuPont and plastic and fuel had something to do with the initial movement to make marijuana illegal
    supposedly it is cheaper to make plastic and fuel from hemp
    and if that process was used then they would have to find another way to dispose of the oil by products they use to make plastic and that would of raised the cost to produce fuels and oils
    dont remember where i read it but ill look for it
    http://www.ozarkia.net/bill/pot/blunderof37.html
    http://www.illuminati-news.com/marijuana-conspiracy.htm
     
  17. May 16, 2014 #17

    7greeneyes

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    Heard the same here, Trollmaster5k
     
  18. May 17, 2014 #18

    ston-loc

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    :stoned: gonna need to read this again sober haha
     
  19. May 22, 2014 #19

    greenfriend

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    You *CANNOT* use heat alone to isolate the cannabinoids and terpenes in cannabis. That is basic organic chem folks. The entire article is entirely **, and doesn't cite a single source to back their claims.

    FYI Rosebud, the US govt does not hold a patent on CBD. The Supreme Court has always held that no one may patent a naturally occurring compound.
     
  20. May 22, 2014 #20

    7greeneyes

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    @ greenfriend Then please tell us the proper way to extract these.

    You yourself are not citing sources to disprove it.
     

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