I try to have the exhaust just a little bit bigger than the intake. This ensures that all the air is being removed from the room and not wafting back out the door when I enter. I think it is called negative air pressure when this happens.
I like to exchange the air in my room 3-4 times a minute. I also have larger exhaust fans than intake fans. If you have a small space, you may be able to use a passive intake.