i use a fan controller, so i lower the cfm intake when the lights are off, but generally one would assume, that the plants dont really use co2 without light, negating the need for nighttime ventilation, but this is inaccurate.
Ventilation, while the lights are off is about the best way to combat mold, it will help keep humidity down and otherwise discourage mold growth all together. Not saying it cant happen, but just leave the fan on, its only beneficial.