For me the important thing is a clean razor blade. I use a fresh one and dip in iso alcohol between each cutting, keep it sterile. I use dip n gro as a hormone compound and rooter cubes. I have also done directly in dirt. I put them on a tray with humidity dome and gentle heat from below. I normally will take 2x as many clones as I know I need. Then I take the strongest, most healthy ones and kill the rest.